DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytes
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference50 articles.
1. Biotransformation of xenobiotics;Parkinson,2001
2. Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies;Poso;Mini Rev Med Chem,2006
3. Phthalate induction of CYP3A4 is dependent on glucocorticoid regulation of PXR expression;Cooper;Toxicol Sci,2008
4. Cytochrome P-450 3A4: regulation and role in drug metabolism;Guengerich;Annu Rev Pharmacol Toxicol,1999
5. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions;Lehmann;J Clin Invest,1998
Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Overcoming ABCB1-mediated multidrug resistance by transcription factor BHLHE40;Neoplasia;2023-05
2. DEC1 negatively regulates CYP2B6 expression by binding to the CYP2B6 promoter region ascribed to IL-6-induced downregulation of CYP2B6 expression in HeLa cells;Xenobiotica;2021-11-28
3. Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP 1 and Other Genes Within a Three‐Dimensional Chromatin Network;Arthritis & Rheumatology;2020-03-30
4. Impact of the inhibition of proteins activities and the chemical aspect of polyphenols-proteins interactions;PharmaNutrition;2019-03
5. Carboxylesterases: Pharmacological Inhibition Regulated Expression and Transcriptional Involvement of Nuclear Receptors and other Transcription Factors;Nuclear Receptor Research;2019
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3