Model systems for the discovery and development of antiarrhythmic drugs

Author:

Nattel Stanley,Duker Göran,Carlsson Leif

Publisher

Elsevier BV

Subject

Molecular Biology,Biophysics

Reference95 articles.

1. Anonymous, 2005. ICH S7B: the nonclinical evaluation of the potential for delayed ventricular repolarization (QT interval prolongation) by human pharmaceuticals London, 12 May 2005. http://www.ich.org/LOB/media/MEDIA2192.pdf.

2. Drug-induced spatial dispersion of repolarization;Antzelevitch;Cardiology Journal,2008

3. Assessing predictors of drug-induced torsades de pointes;Belardinelli;Trends in Pharmacological Sciences,2003

4. Application of large-scale transiently transfected cells to functional assays of ion channels: different targets and assay formats;Bianchi;ASSAY and Drug Development Technologies,2007

5. The cardiac sarcolemmal ATP-sensitive potassium channel as a novel target for anti-arrhythmic therapy;Billman;Pharmacology & Therapeutics,2008

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