Structural insights into the critical DNA damage sensors DNA-PKcs, ATM and ATR

Author:

Baretic Domagoj,Maia de Oliveira Taiana,Niess Martina,Wan Paul,Pollard Hannah,Johnson Christopher M.,Truman Caroline,McCall Eileen,Fisher David,Williams Roger,Phillips Christopher

Funder

MRC

AstraZeneca/LMB Blue Skies Initiative

Publisher

Elsevier BV

Subject

Molecular Biology,Biophysics

Reference50 articles.

1. Insights into Rad3 kinase recruitment from the crystal structure of the DNA damage checkpoint protein Rad26;Andersen;J. Biol. Chem.,2017

2. ATM and ATR signaling at a glance;Awasthi;J. Cell Sci.,2015

3. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation;Bakkenist;Nature,2003

4. Tor forms a dimer through an N-terminal helical solenoid with a complex topology;Baretić;Nat. Commun.,2016

5. PIKKs — the solenoid nest where partners and kinases meet;Baretic;Curr. Opin. Struct. Biol.,2014

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