β-hydroxy-β-methylbutyrate (HMB) improves mitochondrial function in myocytes through pathways involving PPARβ/δ and CDK4

Author:

Zhong Yinzhao,Zeng Liming,Deng Jinping,Duan YehuiORCID,Li Fengna

Funder

Guangdong Province Key Laboratory of Animal Nutritional Regulation

National Key R & D Program

Youth Innovation Promotion Association CAS

Science and Technology Projects of Hunan Province

Key Project of Research and Development Plan of Hunan Province

Youth Innovation Team Project of ISA

Earmarked Fund for China Agriculture Research System

Guangdong Academy of Science

Major Project for Changsha City

Publisher

Elsevier BV

Subject

Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism

Reference46 articles.

1. Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions;Joseph;Exp Diabets Res,2014

2. Skeletal muscle mitochondria: a major player in exercise, health and disease;Russell;Biochim Biophys Acta,2014

3. beta-Hydroxy-beta-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health;He;Amino Acids,2016

4. Fiber hypertrophy and increased oxidative capacity can occur simultaneously in pig glycolytic skeletal muscle;Scheffler;Am J Physiol Cell Physiol,2014

5. Leucine treatment enhances oxidative capacity through complete carbohydrate oxidation and increased mitochondrial density in skeletal muscle cells;Vaughan;Amino Acids,2013

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