The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Developmental Biology
Reference162 articles.
1. Ligand recognition by αβ T cell receptors;Davis;Annu. Rev. Immunol.,1998
2. Human TCR-binding affinity is governed by MHC class restriction;Cole;J. Immunol.,2007
3. A direct estimate of the human t cell receptor diversity;Arstila;Science,1999
4. A very high level of crossreactivity is an essential feature of the T-cell receptor;Mason;Immunol. Today,1998
5. Why must T cells be cross-reactive?;Sewell;Nat. Rev. Immunol.,2012
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