Reduced water exchange in sickle cell anemia red cells: a membrane abnormality
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Biochemistry,Biophysics
Reference48 articles.
1. Abnormalities in membrane phospholipid organization in sickled erythrocytes.
2. Studies on sickled erythrocytes provide evidence that the asymmetric distribution of phosphatidylserine in the red cell membrane is maintained by both ATP-dependent translocation and interaction with membrane skeletal proteins
3. Accelerated transbilayer movement of phosphatidylcholine in sickled erythrocytes. A reversible process.
4. Uncoupling of the membrane skeleton from the lipid bilayer. The cause of accelerated phospholipid flip-flop leading to an enhanced procoagulant activity of sickled cells.
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