Modelling of interaction of basic lipophilic ligands with cytochrome P-450 reconstituted in liposomes. Determination of membrane partition coefficients of S-( − )-nicotine and N,N-diethylaniline from spectral binding studies and fluorescence quenching
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Biochemistry,Biophysics
Reference62 articles.
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1. Compound lipophilicity for substrate binding to human P450s in drug metabolism;Drug Discovery Today;2004-06
2. Quantifying molecular partition into model systems of biomembranes: an emphasis on optical spectroscopic methods;Biochimica et Biophysica Acta (BBA) - Biomembranes;2003-06
3. N-OXIDATIVE TRANSFORMATION OF FREE ANDN-SUBSTITUTED AMINE FUNCTIONS BY CYTOCHROME P450 AS MEANS OF BIOACTIVATION AND DETOXICATION;Drug Metabolism Reviews;2002-01
4. Influence of membrane partitioning on inhibitors of membrane‐bound enzymes;Journal of Pharmaceutical Sciences;2001-11
5. Influence of membrane partitioning on inhibitors of membrane-bound enzymes;Journal of Pharmaceutical Sciences;2001-11
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