Chemical hepatocarcinogenesis in transgenic mice overexpressing mature TGFβ-1 in liver

Author:

Schnur J,Nagy P,Sebestyén A,Schaff Z,Thorgeirsson S.S

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference30 articles.

1. Transforming growth factor-β;Alevizopoulos;Bio Essays,1997

2. Role of TGF-beta in normal differentiation and oncogenesis in rat liver;Nagy;Mol. Carcinogenesis.,1989

3. Constitutive expression of mature transforming growth factor β1 in the liver accelerates hepatocarcinogenesis in transgenic mice;Factor;Cancer Res.,1997

4. Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion;Glick;Proc. Natl. Acad. Sci. USA,1993

5. Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor β receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-Dimethylbenz-(alpha)-anthracene;Böttinger;Cancer Res.,1997

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