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Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family

  • Published:2000-06 Issue:1 Volume:40 Page:339-349
  • ISSN:0065-2571
  • Container-title:Advances in Enzyme Regulation
  • language:en
  • Short-container-title:Advances in Enzyme Regulation

Author:

Keppler Dietrich,Kamisako Toshinori,Leier Inka,Cui Yunhai,Nies Anne T,Tsujii Hiroyuki,König Jörg

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology,Molecular Medicine

Reference46 articles.

1. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein;Jedlitschky;Cancer Res.,1994

2. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates;Leier;J. Biol. Chem.,1994

3. Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport;Müller;Proc. Natl. Acad. Sci. USA,1994

4. Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump;Jedlitschky;Cancer Res.,1996

5. ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids;Loe;J. Biol. Chem.,1996

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