Enhanced oral bioavailability of silybin by a supersaturatable self-emulsifying drug delivery system (S-SEDDS)

Author:

Wei Yinghui,Ye Xiaoli,Shang Xiaoguang,Peng Xuan,Bao Qiang,Liu Minchen,Guo Manman,Li Fanzhu

Publisher

Elsevier BV

Subject

Colloid and Surface Chemistry

Reference27 articles.

1. Silybin and silymarin – new effects and applications;Křen;Biomed. Papers,2005

2. Formulation and biopharmaceutical evaluation of silymarin using SMEDDS;Woo;Arch. Pharm. Res.,2007

3. Analysis of silibinin in rat plasma and bile for hepatobiliary excretion and oral bioavailability application;Wu;Pharm. Biomed. Anal.,2007

4. A new inclusion complex of silibinin and beta-cyclodextrins: in vitro dissolution kinetics and in vivo absorption in comparison with traditional formulations;Arcari;Boll. Chim. Farm.,1992

5. Preparation of silybin–phospholipid complex and its bioavailability in rats;Xiao;Acta Pharmacol. Sin.,2005

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