Chromatographic removal combined with heat, acid and chaotropic inactivation of four model viruses

Author:

Valdés R,Ibarra Neysi,Ruibal I,Beldarraı́n A,Noa E,Herrera N,Alemán R,Padilla S,Garcia J,Pérez M,Morales R,Chong E,Reyes B,Quiñones Y,Agraz A,Herrera L

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference15 articles.

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2. Immunoaffinity purification of recombinant hepatitis B surface antigen from yeast using a monoclonal antibody;Agraz;J. Chromatogr. A,1994

3. The European Agency for the Evaluation of Medical Products, Human Medicines Evaluation Unit-CPMP Biotechnology Working Party, ‘Note for Guidance on Virus Validation Studies: the Design, Contribution, and Interpretation of Studies Validating the Inactivation of Studies Validating the Inactivation and Removal of Viruses,’ (CPMP/BWP/268/95 Final Version 2, Canary Wharf, London, 1996).

4. Process validation for virus removal. Considerations for design of process studies and viral assays;Darling;Biopharm,1996

5. Antigen recognition characteristics and comparative performance in immunoaffinity purification of two monoclonal antibodies specific for the hepatitis B virus surface antigen;Fernández de Cossı́o;J. Biotechnol.,1997

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