Both a reduced acute insulin response to glucose and lower glucose effectiveness are responsible for the worsening of intravenous glucose tolerance in healthy subjects independently of the degree of obesity

Author:

Araújo-Vilar David,García-Estévez Daniel A.,Cabezas-Cerrato José

Publisher

Elsevier BV

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference54 articles.

1. Toward physiological understanding of glucose tolerance;Bergman,1985

2. Quantification of the relationship between insulin sensitivity and β-cell function in human subjects;Kahn,1993

3. Importance of glucose per se to intravenous glucose tolerance: Comparison of the minimal model prediction with direct measurements;Ader;Diabetes,1985

4. The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects;Kahn;Diabetes,1994

5. Glucose effectiveness in two subtypes with impaired glucose tolerance. A minimal model analysis;Taniguchi;Diabetes,1994

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