Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer

Author:

Juanpere Nuria,Agell Laia,Lorenzo Marta,de Muga Silvia,López-Vilaró Laura,Murillo Raquel,Mojal Sergi,Serrano Sergio,Lorente José A.,Lloreta Josep,Hernández Silvia

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference31 articles.

1. Bladder cancer;Kaufman;Lancet,2009

2. Bladder cancer;Morgan;Curr Opin Oncol,2011

3. FGFR3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder;Bakkar;Cancer Res,2003

4. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors;Billerey;Am J Pathol,2001

5. Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder;Cappellen;Oncogene,1997

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