Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix-Reference-Cited by-同舟云学术

Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix

Published:2014-02 Issue:2 Volume:45 Page:227-235
ISSN:0046-8177
Container-title:Human Pathology
language:en
Short-container-title:Human Pathology

Author:

Pai Rish K.,Hartman Douglas J.,Gonzalo David H.,Lai Keith K.,Downs-Kelly Erinn,Goldblum John R.,Liu Xiuli,Patil Deepa T.,Bennett Ana E.,Plesec Thomas P.,Kuan Shih-Fan,Nikiforova Marina N.,Shadrach Bonnie,Pai Reetesh K.

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference27 articles.

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3. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines;Kane;Cancer Res,1997

4. BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum;Kambara;Gut,2004

5. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer;Weisenberger;Nat Genet,2006

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