Integrating microsecond timescale classical and biased molecular dynamics simulations to screen potential molecules for BRD4-BD1
Author:
Publisher
Elsevier BV
Subject
General Mathematics,General Physics and Astronomy,Statistical and Nonlinear Physics,Applied Mathematics
Reference61 articles.
1. Acetylation and methylation of histones and their possible role in regulation of RNA synthesis;Allfrey;Proc Natl Acad Sci U S A,1964
2. Chemical studies of histone acetylation: the occurrence of ε-N-acetyllysine in the f2a1 histone;Gershey;J Biol Chem,1968
3. The bromodomain: a chromatin-targeting module?;Winston;Nat Struct Biol,1999
4. Structure and ligand of a histone acetyltransferase bromodomain;Dhalluin;Nature,1999
5. Lysine acetylation targets protein complexes and co-regulates major cellular functions;Choudhary;Science,2009
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