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5. Fundings:1. China Medical and Health Development Foundation, Young and Middle-aged Doctors Excellent Talent, Pei Ying Program, Clinical study on prevention and treatment of exocrine pancreatic insufficiency associated with severe acute pancreatitis. 2. Tianjin Nankai Hospital integrated Traditional Chinese and Western medicine prevention and treatment key technology and program optimization 2022 key project,A multi-omics study of the microenvironment of abdominal inflammation in acute pancreatitis based on minimally invasive individualized integrated traditional Chinese and Western Medicine surgical treatment system, NKYY-IIT-2022-009-2. 3. Tianjin key areas of traditional Chinese medicine science and technology project,Clinical study of combined treatment of TCM and Western medicine with pancreato-intestinal therapy based on peritoneal microecology in the treatment of acute pancreatitis 2022005. 4. Tianjin Natural Science Foundation key project, Establishment of individualized surgical treatment system for severe acute pancreatitis and intelligent evaluation of multimodal imaging. 5. Tianjin Administration of Traditional Chinese Medicine fund of traditional Chinese and Western medicine integrated research project,Study on the change of peritoneal microecology in acute pancreatitis and the effect of Qingyi Decoction 2021006. 6. Tianjin 131 innovative talent team, innovation team for Diagnosis and treatment of acute abdomen related to biliary and pancreatic diseases201938.