Mechanical strain induces a pro-fibrotic phenotype in human mitral valvular interstitial cells through RhoC/ROCK/MRTF-A and Erk1/2 signaling pathways-Reference-Cited by-同舟云学术

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Mechanical strain induces a pro-fibrotic phenotype in human mitral valvular interstitial cells through RhoC/ROCK/MRTF-A and Erk1/2 signaling pathways

Published:2019-10 Issue: Volume:135 Page:149-159
ISSN:0022-2828
Container-title:Journal of Molecular and Cellular Cardiology
language:en
Short-container-title:Journal of Molecular and Cellular Cardiology

Author:

Blomme Benoit,Deroanne Christophe,Hulin Alexia,Lambert Charles,Defraigne Jean-Olivier,Nusgens Betty,Radermecker Marc,Colige Alain

Funder

J. Grommersch Award and Prodex/Belgian Science Policy

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Molecular Biology

Reference54 articles.

1. Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis;Merryman;Am. J. Physiol. Heart Circ. Physiol.,2006

2. Heart valve biomechanics and underlying mechanobiology;Ayoub;Compr. Physiol.,2016

3. Heart disease and stroke statistics—2013 update: a report from the American Heart Association;Go;Circulation,2013

4. Mitral valve prolapse;Guy;Annu. Rev. Med.,2012

5. Comparative histopathological analysis of mitral valves in Barlow disease and fibroelastic deficiency;Hjortnaes;Semin. Thorac. Cardiovasc. Surg.,2016

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