Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway-Reference-Cited by-同舟云学术

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Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway

Published:2017-07 Issue: Volume:108 Page:170-180
ISSN:0022-2828
Container-title:Journal of Molecular and Cellular Cardiology
language:en
Short-container-title:Journal of Molecular and Cellular Cardiology

Author:

Jin Huiling,Fujita Takayuki,Jin Meihua,Kurotani Reiko,Namekata Iyuki,Hamaguchi Shogo,Hidaka Yuko^ORCID,Cai Wenqian,Suita Kenji,Ohnuki Yoshiki,Mototani Yasumasa,Shiozawa Kouichi,Prajapati Rajesh,Liang Chen,Umemura Masanari,Yokoyama Utako,Sato Motohiko,Tanaka Hikaru,Okumura Satoshi,Ishikawa Yoshihiro

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

MEXT-Supported Program for the Strategic Research Foundation at Private Universities

Japan Agency for Medical Research and Development

Strategic Research Promotion of Yokohama City University

Naito Foundation

Senshin Medical Research Foundation

Pfizer Japan

Research Foundation for Community Medicine

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Molecular Biology

Reference64 articles.

1. The epidemiology of sepsis in the United States from 1979 through 2000;Martin;N. Engl. J. Med.,2003

2. Endotoxin-induced myocardial dysfunction: effects of macrophage migration inhibitory factor neutralization;Chagnon;Circ. Res.,2005

3. Molecular events in the cardiomyopathy of sepsis;Flierl;Mol. Med.,2008

4. Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura;Girardin;N. Engl. J. Med.,1988

5. Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum;Kumar;J. Exp. Med.,1996

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2. Electroacupuncture pre-treatment alleviates sepsis-induced cardiac inflammation and dysfunction by inhibiting the calpain-2/STAT3 pathway;Frontiers in Physiology;2022-09-07

3. Epac: A Promising Therapeutic Target for Vascular Diseases: A Review;Frontiers in Pharmacology;2022-07-14

4. Unraveling the role of Epac1‐SOCS3 signaling in the development of neonatal‐ CRD ‐induced visceral hypersensitivity in rats;CNS Neuroscience & Therapeutics;2022-06-15

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