Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation

Author:

Soler Amanda,Hunter Ian,Joseph Gregory,Hutcheson Rebecca,Hutcheson Brenda,Yang Jenny,Zhang Frank Fan,Joshi Sachindra Raj,Bradford Chastity,Gotlinger Katherine H.,Maniyar Rachana,Falck John R.,Proctor Spencer,Schwartzman Michal Laniado,Gupte Sachin A.,Rocic Petra

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine,Molecular Biology

Reference94 articles.

1. Arterial stiffness and hypertension: chicken or egg?;Mitchell;Hypertension,2014

2. Extracellular matrix alterations in hypertensive vascular remodeling;Lemarié;J. Mol. Cell. Cardiol.,2010

3. Elastin in large artery stiffness and hypertension;Wagenseil;J. Cardiovasc. Transl. Res.,2012

4. Remote exosites of the catalytic domain of matrix metalloproteinase-12 enhance elastin degradation;Fulcher;Biochemistry,2011

5. Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening;Liu;Sci. Rep.,2015

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