C-1311 (Symadex), a potential anti-cancer drug, intercalates into DNA between A and G moieties. NMR-derived and MD-refined stereostructure of the d(GAGGCCTC) 2 :C-1311 complex-Reference-Cited by-同舟云学术

C-1311 (Symadex), a potential anti-cancer drug, intercalates into DNA between A and G moieties. NMR-derived and MD-refined stereostructure of the d(GAGGCCTC) 2 :C-1311 complex

Published:2017-08 Issue: Volume:1141 Page:357-367
ISSN:0022-2860
Container-title:Journal of Molecular Structure
language:en
Short-container-title:Journal of Molecular Structure

Author:

Laskowski Tomasz,Borzyszkowska Julia,Grynda Jakub,Mazerski Jan

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference24 articles.

1. Structure−activity relationship for antineoplastic imidazoacridinones: synthesis and antileukemic activity in vivo;Cholody;J. Med. Chem.,1996

2. Chromophore-modified antineoplastic imidazoacridinones. Synthesis and activity against murine leukemias;Cholody;J. Med. Chem.,1992

3. 5-[(Aminoalkyl)amino]imidazo[4,5,1-de]acridin-6-ones as a novel class of antineoplastic agents. Synthesis and biological activity;Cholody;J. Med. Chem.,1990

4. Imidazoacridinones arrest cell-cycle progression in the G2 phase of L1210 cells;Augustin;Cancer Chemother. Pharmacol.,1996

5. Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer;Burger;Br. J. Cancer,1996

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The interactions of monomeric acridines and unsymmetrical bisacridines (UAs) with DNA duplexes: an insight provided by NMR and MD studies;Scientific Reports;2023-03-01

2. A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships;European Journal of Medicinal Chemistry;2022-09

3. Acid–Base Equilibrium and Self-Association in Relation to High Antitumor Activity of Selected Unsymmetrical Bisacridines Established by Extensive Chemometric Analysis;Molecules;2022-06-21

4. c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells;International Journal of Molecular Sciences;2022-03-11

5. A strong preference for the TA/TA dinucleotide step discovered for an acridine-based, potent antitumor dsDNA intercalator, C-1305: NMR-driven structural and sequence-specificity studies;Scientific Reports;2020-07-16