Design, synthesis, and biological evaluation of selenium-containing small molecule compounds based on the dual mechanism of fungal CYP51 inhibition and fungal ROS generation

Author:

Guo Meng-bi,Xu Hang,Yan Zhong-zuo,Wang Xin,Su Xin,Guo Chun,Hou ZhuangORCID,Gong Ping

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference23 articles.

1. Tackling human fungal infections;Brown;Science,2012

2. A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise;Howard;Chem. Soc. Rev.,2020

3. Fosmanogepix: a review of the first-in-class broad spectrum agent for thetreatment of invasive fungal infections;Shaw;J. Fungi,2020

4. The future of antifungal drug therapy: novel compounds and targets;Fernandes;Antimicrob. Agents Chemother.,2021

5. Azole antifungals: 35 years of invasive fungal infection management;Allen;Expert Rev. Antiinfect.Ther.,2015

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