Synthesis and biological (in vitro and in silico) screening of the 4-aryl-fused pyranopyrazole derivatives as enzyme (α-amylase, α-glucosidase, acetylcholinesterase & proteinase) inhibitors with anti-oxidant and cytotoxic activities

Author:

Abdelazeem Nagwa M.,Aboulthana Wael MahmoudORCID,Elshahid Zeinab A.,El-Hussieny MarwaORCID,Al-Ashmawy Aisha A.K.ORCID

Funder

National Research Centre

Publisher

Elsevier BV

Reference55 articles.

1. Design, synthesis, computational and biological evaluation of some new hydrazino derivatives of DHA and pyranopyrazoles;Kumar;Eur. J. Med. Chem.,2012

2. Pyrazolopyranopyrimidines as a class of anti-inflammatory agents;Zaki;Z. Naturforsch. C J. Biosci.,2006

3. A clean and one-pot synthesis of spiroindoline-pyranopyrazoles;Ahadi;J. Heterocycl. Chem.,2010

4. Bioactive and pharmacologically important pyrano [2, 3-c] pyrazoles;Das;J. Chem. Pharm. Res.,2014

5. Design, an efficient ecofriendly synthesis of spirooxindole derivatives and their anticancer activity supported by molecular docking studies;Erugu;World J. Pharm. Pharm. Sci.,2014

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