Combining AI and traditional screening for discovery of a potent ROCK2 inhibitor against lymphoma

Author:

Lu Yan,Shen Zheyuan,Shen Liteng,Ying JiaxunORCID,Gao Jian,Zhao Jingyi,Geng Shuangshuang,Chi Xinglong,Zhang Tianshu,Xu Lei,Zhang Qingnan,Dong Xiaowu,Xu Donghang

Publisher

Elsevier BV

Reference52 articles.

1. RhoA/Rho-kinase in the cardiovascular system;Shimokawa;Circ. Res.,2016

2. Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions;Julian;Small GTPases,2014

3. Roles of Rho-associated coiled-coil protein kinase in multiple cell behaviors;Liu;Zhongguo Yi Xue Ke Xue Yuan Xue Bao,2012

4. Rho kinases in embryonic development and stem cell research;Shi;Arch. Immunol. Ther. Exp.,2022

5. The physiology, pathology, and therapeutic interventions for ROCK isoforms in diabetic kidney disease;Matoba;Front. Pharmacol.,2020

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