Synthesis, crystal structure, DFT study, Hirshfeld surface analysis, molecular docking and antitumor activity of a novel SHP2 inhibitor-Reference-Cited by-同舟云学术

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Synthesis, crystal structure, DFT study, Hirshfeld surface analysis, molecular docking and antitumor activity of a novel SHP2 inhibitor

Published:2024-04 Issue: Volume:1301 Page:137320
ISSN:0022-2860
Container-title:Journal of Molecular Structure
language:en
Short-container-title:Journal of Molecular Structure

Author:

Song Wenting,Li Li,Liao Tianhui,Chen Dongmei,Jia Yihe,Zhao Xin,Zheng Zhaopeng,Zhou Zhixu^ORCID

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference43 articles.

1. PD-1/SHP-2 inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment;Li;Cancer Res.,2015

2. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition;Hui;Science,2017

3. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors;Wu;Oncogene,2001

4. Receptor-specific regulation of phosphatidylinositol 3′-kinase activation by the protein tyrosine phosphatase Shp2;Zhang;Mol. Cell. Biol.,2002

5. Regulation of the mitogen-activated protein kinase signaling pathway by SHP2;Cunnick;J. Biol. Chem.,2002

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