Partition coefficients and thermodynamics of transfer of novel drug-like spiro-derivatives in model biological solutions

Author:

Blokhina Svetlana V.,Ol’khovich Marina V.,Sharapova Angelica V.,Proshin Alexey N.,Perlovich German L.

Publisher

Elsevier BV

Subject

Physical and Theoretical Chemistry,General Materials Science,Atomic and Molecular Physics, and Optics

Reference17 articles.

1. Octanol-water Partition Coeffcients: Fundamentals and Physical Chemistry;Sangster,1997

2. Lipophilicity in Drug Action and Toxicology;Pliška,2008

3. Druglike Properties: Concepts, Structure Design and Methods;Kerns,2008

4. Free Energy Perturbation Study of Octanol/Water Partition Coefficients:  Comparison with Continuum GB/SA Calculations

5. Calculation of Drug Lipophilicity: The Hydrophobic Fragmental Constant Approach;Rekker,1992

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