Local delivery of a senolytic drug in ischemia and reperfusion-injured heart attenuates cardiac remodeling and restores impaired cardiac function

Author:

Lee Ju-RoORCID,Park Bong-Woo,Park Jae-Hyun,Lim Songhyun,Kwon Sung Pil,Hwang Ji-WonORCID,Kim Hyeok,Park Hun-Jun,Kim Byung-Soo

Funder

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Molecular Biology,Biomedical Engineering,Biochemistry,Biomaterials,General Medicine,Biotechnology

Reference56 articles.

1. Left-ventricular remodeling after acute myocardial-infarction;Pfeffer;Annu. Rev. Med.,1995

2. Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations;Hausenloy;Eur. Heart J.,2017

3. 5-year prognostic value of no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction;Ndrepepa;J. Am. Coll. Cardiol.,2010

4. Myocardial reperfusion injury;Yellon;N. Engl. J. Med.,2007

5. Past, present, and future of acute heart failure clinical trials-a high-risk population in search of a strategy;Butler;Eur. J. Heart Fail.,2018

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