Development of conjugated estrogens/bazedoxifene, the first tissue selective estrogen complex (TSEC) for management of menopausal hot flashes and postmenopausal bone loss

Author:

Komm Barry S.,Mirkin Sebastian,Jenkins Simon N.

Funder

Pfizer

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry

Reference90 articles.

1. Duavee [package insert]. Philadelphia, PA: Wyeth Pharmaceuticals Inc, A subsidiary of Pfizer Inc.; 2013.

2. The 2012 hormone therapy position statement of: The North American Menopause Society;Menopause,2012

3. Incidence of endometrial hyperplasia in postmenopausal women taking conjugated estrogens (Premarin) with medroxyprogesterone acetate or conjugated estrogens alone. The Menopause Study Group;Woodruff;Am J Obstet Gynecol,1994

4. Hormone replacement therapy in postmenopausal women: endometrial hyperplasia and irregular bleeding;Lethaby;Cochrane Database Syst Rev,2004

5. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the women’s health initiative randomized trials;Manson;JAMA,2013

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