Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression

Author:

Shafi Ayesha A.,Cox Marc B.,Weigel Nancy L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry

Reference29 articles.

1. Identification of a clinically relevant androgen-dependent gene signature in prostate cancer;Heemers;Cancer Res,2011

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3. Androgen receptor action in hormone-dependent and recurrent prostate cancer;Agoulnik;J Cell Biochem,2006

4. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy;Ryan;J Clin Oncol,2010

5. Effect of MDV3100 an androgen receptor signaling inhibitor (ARSI) on overall survival in patients with prostate cancer postdocetaxel results from the phase III AFFIRM study;Scher;J Clin Oncol,2012

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