New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells

Author:

Garcia Israel José Pereira,de Oliveira Gisele Capanema,de Moura Valadares Jéssica Martins,Banfi Felipe Finger,Andrade Silmara Nunes,Freitas Túlio Resende,dos Santos Monção Filho Evaldo,Lima Santos Hérica de,Júnior Gerardo Magela Vieira,Chaves Mariana Helena,de Jesus Rodrigues Domingos,Sanchez Bruno Antonio Marinho,Varotti Fernando P.ORCID,Barbosa Leandro Augusto

Funder

FAPEMIG

FAPEMAT

CAPES

CNPq

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry

Reference66 articles.

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3. The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking;Liu;BBA,2010

4. Intracellular reactive oxygen species mediate the linkage of Na+/K+-ATPase to hypertrophy and its marker genes in cardiac myocytes;Xie;J. Biol. Chem.,1999

5. Involvement of Src and epidermal growth factor receptor in the signal-transducing function of Na+/K+-ATPase;Haas;J. Biol. Chem.,2000

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