Synthesis of 21-nitrogen substituted pregna-5,17(20)-dienes from pregnenolone-Reference-Cited by-同舟云学术

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Synthesis of 21-nitrogen substituted pregna-5,17(20)-dienes from pregnenolone

Published:2012-01 Issue:1-2 Volume:77 Page:77-84
ISSN:0039-128X
Container-title:Steroids
language:en
Short-container-title:Steroids

Author:

Stulov Sergey V.,Tkachev Yaroslav V.,Novikov Roman A.,Zavialova Maria G.,Timofeev Vladimir P.,Misharin Alexander Yu.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry

Reference49 articles.

1. Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development;Bruno;Bioorg Med Chem,2007

2. CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets;Hakki;Pharmacol Ther,2006

3. Inhibitors of 17α-hydroxylase/17, 20-lyase (CYP17) potential agents for the treatment of prostate cancer;Njar;Curr Pharm Des,1999

4. Synthesis and evaluation of pregnane derivatives as inhibitors of human testicular 17α-hydroxylase;Li;J Med Chem,1996

5. Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model;Handratta;J Med Chem,2005

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2. Design and Synthesis of New Agents for Prostate Cancer Treatment Inspired by Steroidal CYP17 A1 Inhibitors;ChemistrySelect;2022-12

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5. Recent Progress of Novel Steroid Derivatives and Their Potential Biological Properties;Mini-Reviews in Medicinal Chemistry;2018-04-30

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