Single-strand nicking of DNA in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action
Author:
Publisher
Elsevier BV
Subject
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Reference30 articles.
1. Primary Structure of Neocarzinostatin, an Antitumor Protein
2. The relationship between DNA strand-scission and DNA synthesis inhibition in HeLa cells treated with neocarzinostatin
3. Mode of action of neocarzinostatin: Inhibition of DNA synthesis and degradation of DNA in Sarcina lutea
4. DNA strand scission by the antitumor protein neocarzinostatin
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1. Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy;Cancer Chemotherapy and Pharmacology;2008-03-13
2. Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2;Cancer Chemotherapy and Pharmacology;2005-07-05
3. Exploiting Oxidative Stress and Signaling in Chemotherapy of Resistant Neoplasms;Biochemistry (Moscow);2004-01
4. Development of an Enantioselective Synthetic Route to Neocarzinostatin Chromophore and Its Use for Multiple Radioisotopic Incorporation;Journal of the American Chemical Society;2002-04-19
5. Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein- chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure;Proceedings of the National Academy of Sciences;2001-09-18
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