Evaluation of the sensitivity of R1ρ MRI to pH and macromolecular density

Author:

Ali Syed O.,Fessas PetrosORCID,Kaggie Joshua D.,Zaccagna FulvioORCID,Houston Gavin,Reid Scott,Graves Martin J.,Gallagher Ferdia A.

Funder

Cancer Research UK

GlaxoSmithKline

CRUK

National Institute of Health Research

Engineering and Physical Sciences Research Council

Addenbrooke's Charitable Trust

Cambridge Experimental Cancer Medicine Centre

National Institute for Health Research

Cambridge University Hospitals

Publisher

Elsevier BV

Subject

Radiology, Nuclear Medicine and imaging,Biomedical Engineering,Biophysics

Reference47 articles.

1. Tumor pH and its measurement;Zhang;J Nucl Med,2010

2. Extracellular proton concentrations impacts LN229 glioblastoma tumor cell fate via differential modulation of surface lipids;John;Front Oncol,2017

3. Acidic extracellular microenvironment and cancer;Kato;Cancer Cell Int,2013

4. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism;Helmlinger;Clin Cancer Res,2002

5. Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo;Fukumura;Cancer Res,2001

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