Parkin-linked Parkinson’s disease: From clinical insights to pathogenic mechanisms and novel therapeutic approaches

Author:

Wasner Kobi,Grünewald Anne,Klein Christine

Funder

Fonds National de la Recherche Luxembourg

Deutsche Forschungsgemeinschaft

H2020 European Research Council

Publisher

Elsevier BV

Subject

General Medicine,General Neuroscience

Reference40 articles.

1. The transcription factor function of Parkin: breaking the dogma;Alves da Costa;Front. Neurosci.,2018

2. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease;Bender;Nat. Genet.,2006

3. Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy;Bernardini;EMBO J.,2019

4. Borsche, M., König, I.R., Delcambre, S., Petrucci, S., Balck, A., Brüggemann, N., Zimprich, A., Wasner, K., Pereira, S.L., Avenali, M., Deuschle, C., Badanjak, K., Ghelfi, J., Gasser, T., Kasten, M., Rosenstiel, P., Lohmann, K., Brockmann, K., Valente, E.M., Youle, R.J., Grünewald, A., Klein, C., in press. Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism. Brain.

5. Deep brain stimulation in patients with mutations in Parkinson’s disease-related genes: a systematic review;de Oliveira;Mov. Disord. Clin. Pract.,2019

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