Kirenol upregulates nuclear Annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats

Author:

Wang Zhe-Ming,Zhu Shi-Gong,Wu Zai-Wang,Lu Yue,Fu Hong-Zheng,Qian Rui-Qin

Funder

Natural Science Foundation of Beijing, China

Comprehensive Platform of Innovative Drug Research and Development of Peking University

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference45 articles.

1. Negative regulation of nuclear factor-kappa B activation and function by glucocorticoids;Almawi;Journal of Molecular Endocrinology,2002

2. Interleukin 6 is required for the development of collagen-induced arthritis;Alonzi;Journal of Experimental Medicine,1998

3. Glucocorticoid resistance in inflammatory diseases;Barnes;The Lancet,2009

4. Macrophage migration inhibitory factor;Baugh;Critical Care Medicine,2002

5. Effect of kirenol on cytokines in serum and apoptosis proteins expression in synoviocytes of adjuvant arthritis rats;Bi;Chinese Traditional and Herbal Drugs,2007

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