A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids-Reference-Cited by-同舟云学术

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A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids

Published:2020-04 Issue: Volume:252 Page:112581
ISSN:0378-8741
Container-title:Journal of Ethnopharmacology
language:en
Short-container-title:Journal of Ethnopharmacology

Author:

Cong Jiaojiao,Ruan Yiling,Lyu Qinglin,Qin Xiaohui,Qi Xinming,Liu Wenyuan,Kang Lifeng,Zhang Junying,Wu Chunyong

Funder

National Natural Science Foundation of China

"Double First-Class" University project

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference36 articles.

1. Synchronized activity of organic cation transporter 3 (Oct3/Slc22a3) and multidrug and toxin extrusion 1 (Mate1/Slc47a1) transporter in transplacental passage of MPP+ in rat;Ahmadimoghaddam;Toxicol. Sci.,2012

2. The effects of Aconitum alkaloids on the central nervous system;Ameri;Prog. Neurobiol.,1998

3. Clonidine transport at the mouse blood-brain barrier by a new H+ antiporter that interacts with addictive drugs;André;J. Cereb. Blood Flow Metab.,2009

4. Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier;Chapy;Br. J. Pharmacol.,2016

5. Multidrug resistance-associated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells;Dai;Life Sci.,2015

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comprehensive insight into the pharmacology, pharmacokinetics, toxicity, detoxification and extraction of hypaconitine from Aconitum plants;Journal of Ethnopharmacology;2024-03

2. Carrier-Mediated Delivery of Low-Molecular-Weight N-Containing Drugs across the Blood–Brain Barrier or the Blood–Retinal Barrier Using the Proton-Coupled Organic Cation Antiporter;Future Pharmacology;2023-10-12

3. Aconitum carmichaelii triggers neurotoxicity and Parkinson‐like symptoms through initiation of ROS‐mitochondrial apoptosis and the Nox5/DJ‐1 signaling pathway;BMEMat;2023-05-06

4. Drug Permeability: From the Blood–Brain Barrier to the Peripheral Nerve Barriers;Advanced Therapeutics;2023-02-09

5. The mystery of the human proton-organic cation antiporter: One transport protein or many?;Pharmacology & Therapeutics;2022-11

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