Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4/xCT signaling pathway

Author:

Zhang Jie,Wang Xinyi,Guan Baoyi,Wang Xue,An Xiaojing,Wang Tong,Chen Xuanye,Zhao Lin,Jia Jundi,Song Luxia,Ma Dan,Li Qiuyi,Zhang He,Ju Jianqing,Xu HaoORCID

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference44 articles.

1. Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell;Bai;Free Radical Biol. Med.,2020

2. Pharmacology Research Methodology of Traditional Chinese Medicine;Chen,2011

3. Tanshinone IIA exerts anti-inflammatory and immune-regulating effects on vulnerable atherosclerotic plaque partially the TLR4/MyD88/NF-κB signal pathway;Chen;Front. Pharmacol.,2019

4. Ferroptosis: an iron-dependent form of nonapoptotic cell death;Dixon;Cell,2012

5. Clicinal study of Qingxin Jieyu decoction for patients with stable coronary heart disease and low-grade systemic inflammation: a randomized, double-blinded and placebo controlled trial;Gao;Zhongguo Zhong Xi Yi Jie He Za Zhi,2022

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