Simultaneous determination of liensinine, isoliensinine and neferine in rat plasma by UPLC–MS/MS and application of the technique to pharmacokinetic studies

Author:

Hu Guoxin,Xu Ren-ai,Dong Yao-yao,Wang Yi-yan,Yao Wen-wen,Chen Zhi-chuan,Chen Dongxin,Bu Tiao,Ge Ren-shan

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference18 articles.

1. Development and validation of a useful UPLC–MS/MS method for quantification of total and phosphorylated-ribavirin in peripheral blood mononuclear cells of HCV+ patients;Agnesod;Journal of Pharmaceutical and Biomedical Analysis,2013

2. Separation, identification and rapid determination of liensine, isoliensinine and neferine from embryo of the seed of Nelumbo nucifera Gaertn. by liquid chromatography coupled to diode array detector and tandem mass spectrometry;Chen;Journal of Pharmaceutical and Biomedical Analysis,2007

3. Assessment of anti-depressant effect of nelumbinis semen on rats under chronic mild stress and its subchronic oral toxicity in rats and beagle dogs;Chung;BMC Complementary and Alternative Medicine,2012

4. Comparative effects of liensinine and neferine on the human ether-a-go-go-related gene potassium channel and pharmacological activity analysis;Dong;Cellular Physiology and Biochemistry: International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology,2012

5. Rapid determination of three alkaloids from Lotus Plumule in human serum using an HPLC–DAD method with a short monolithic column;Du;Food Chemistry,2011

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