Exploring the synergistic mechanism of Gegen Qinlian Decoction on the Wnt signaling pathway using an integrated strategy of network pharmacology and RNA-seq-Reference-Cited by-同舟云学术

Exploring the synergistic mechanism of Gegen Qinlian Decoction on the Wnt signaling pathway using an integrated strategy of network pharmacology and RNA-seq

Published:2021-10 Issue: Volume:278 Page:114283
ISSN:0378-8741
Container-title:Journal of Ethnopharmacology
language:en
Short-container-title:Journal of Ethnopharmacology

Author:

Li Yanping,Gong Yiting,Zhang Xin,Wang Jiaxin,Cheng Yaru,Liu Fen,Shi Xiujia,Xu Wenjuan,Dong Ling

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference40 articles.

1. Dynamical regulation analysis identifies molecular mechanisms of fuzheng-huayu formula against hepatitis B-caused liver cirrhosis;Chen;Evid Based Compl Alt,2015

2. UniProt: a worldwide hub of protein knowledge;Consortium;Nucleic Acids Res.,2019

3. Wnt/β-Catenin-Mediated signaling commonly altered in colorectal cancer;Deitrick;Prog Mol Biol Transl,2016

4. DAVID: database for annotation, visualization, and integrated discovery;Dennis;Genome Biol.,2003

5. Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: a novel strategy for exploring active components and effective mechanism of TCM formulae;Ding;Pharmacol. Res.,2020

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