Exploring therapeutic mechanisms of San-Huang-Tang in nonalcoholic fatty liver disease through network pharmacology and experimental validation

Author:

Shi HuilianORCID,Qiao Fei,Huang Kaiyue,Lu Weiting,Zhang Xinzhuang,Ke Zhipeng,Wu Yanchi,Cao Liang,Chen Yuanyuan

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference46 articles.

1. FoxO1 signaling as a therapeutic target for type 2 diabetes and obesity;Benchoula;Eur. J. Pharmacol.,2021

2. Racial differences in prevalence and severity of non-alcoholic fatty liver disease;Bonacini;World J. Hepatol.,2021

3. Analysis of the correlation between dampness syndrome of traditional Chinese medicine and the degree of nonalcoholic fatty liver;Cheng;Western Traditional Chinese Medicine,2020

4. Traditional Chinese herbs as chemical resource library for drug discovery of anti-infective and anti-inflammatory;Ding;J. Ethnopharmacol.,2014

5. San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1α/PEPCK signaling in obese and galr1 knockout mice models;Fang;J. Ethnopharmacol.,2020

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