Chinese herbal Jianpi Jiedu formula suppressed colorectal cancer growth in vitro and in vivo via modulating hypoxia-inducible factor 1 alpha-mediated fibroblasts activation

Author:

He Shenglan,Hao Lixiao,Chen Youlan,Gong Biao,Xu Xiaowen

Funder

National Natural Science Foundation of China

Shanghai Science and Technology Development Foundation

Publisher

Elsevier BV

Reference66 articles.

1. Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up;Cervantes;Ann. Oncol.,2023

2. Effects of modified Jianpi Jiedu Formula on iintestinal flora and immune function in advanced colorectal cancer chemotherapy with spleen Qi deficiency syndrome;Chen;Chinese Medicine Journal,2020

3. Cancer-associated fibroblast heterogeneity: a factor that cannot Be ignored in immune microenvironment remodeling;Chen;Front. Immunol.,2021

4. Clinical and therapeutic relevance of cancer-associated fibroblasts;Chen;Nat Rev Clin Oncol,2021

5. Turning foes to friends: targeting cancer-associated fibroblasts;Chen;Nat. Rev. Drug Discov.,2019

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