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Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells

  • Published:2020-08 Issue: Volume:255 Page:117846
  • ISSN:0024-3205
  • Container-title:Life Sciences
  • language:en
  • Short-container-title:Life Sciences

Author:

Dong Delu,Dong Yuan,Fu Jiaying,Lu Shengyao,Yuan Chunli,Xia Meihui,Sun Liankun

Funder

National Natural Science Foundation of China

Jilin Province Industrial Innovation Project

Jilin Provincial Research Foundation for the Development of Science and Technology Projects

Fundamental Research Funds for the Central Universities

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference40 articles.

1. Mitochondria and mitochondrial ROS in cancer: novel targets for anticancer therapy;Yang;J. Cell. Physiol.,2016

2. Mitochondria in ageing: there is metabolism beyond the ROS;Breitenbach;FEMS Yeast Res.,2014

3. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release;Zorov;Physiol. Rev.,2014

4. Mitochondria as playmakers of apoptosis, autophagy and senescence;Abate;Semin. Cell Dev. Biol.,2019

5. The role of mitochondria in the oncogenic signal transduction;Frezza;Int. J. Biochem. Cell Biol.,2014
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