Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications

Author:

Banu Nehla,Panikar Sandeep Surendra,Leal Lizbeth Riera,Leal Annie Riera

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference282 articles.

1. Organ-protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID-19;Cheng;J. Med. Virol.,2020

2. Angiotensin converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system;Gheblawi;Circ. Res.,2020

3. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus;Li;Nature,2003

4. Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus;Wan;J. Virol.,2020

5. COVID-19, ACE2, and the cardiovascular consequences;South;Am. J. Physiol. Heart Circ. Physiol.,2020

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