Indole-linked 1,2,3-triazole derivatives efficiently modulate COX-2 protein and PGE2 levels in human THP-1 monocytes by suppressing AGE-ROS-NF-kβ nexus

Author:

Jahan Humera,Siddiqui Nimra Naz,Iqbal Shazia,Basha Fatima Z.,Khan Maria Aqeel,Aslam Tooba,Choudhary M. Iqbal

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference44 articles.

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4. Liraglutide attenuates high glucose-induced abnormal cell migration, proliferation, and apoptosis of vascular smooth muscle cells by activating the GLP-1 receptor, and inhibiting ERK1/2 and PI3K/Akt signaling pathways;Shi;Cardiovasc. Diabetol.,2015

5. High glucose-induced activation of protein kinase signaling pathways in vascular smooth muscle cells: a potential role in the pathogenesis of vascular dysfunction in diabetes (review);Srivastava;Int. J. Mol. Med.,2002

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