Inhibiting C5 in patients with severe COVID-19—the incorrect target?
Author:
Publisher
Elsevier BV
Subject
Pulmonary and Respiratory Medicine
Reference5 articles.
1. Intravenous ravulizumab in mechanically ventilated patients hospitalised with severe COVID-19: a phase 3, multicentre, open-label, randomised controlled trial;Annane;Lancet Respir Med,2023
2. Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial;Vlaar;Lancet Respir Med,2022
3. Complement activation in COVID-19 and targeted therapeutic options: a scoping review;Lim;Blood Rev,2023
4. Complement inhibition in severe COVID-19—blocking C5a seems to be key: author's reply;Annane;EClinicalMedicine,2021
5. The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19;Vlaar;Clin Transl Sci,2022
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Adverse drug reactions associated with COVID-19 management;Naunyn-Schmiedeberg's Archives of Pharmacology;2024-05-14
2. Targeting C5a is beneficial in critically ill COVID-19 patients;Immunobiology;2023-11
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