2-Acetylaminofluorene metabolism in rat liver microsomes: Formation of 9-hydroxy-2-acetylaminofluorene and effect of hepatic enzyme modifiers
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference23 articles.
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3. N-(9-Hydroxy-9H-fluoren-2yl)-acetamide and N-(9-oxo-9H-fluoren-2yl)-acetamide: metabolites of N-(9H-fluoren-2yl)-acetamide;Benkert;Biochem. Pharmacol.,1975
4. (9-14C)-Fluorene hydroperoxide as a possible intermediate in the hydroxylation of (9-14C)-fluorene by rat liver homogenate;Chan;Biochim. Biophys. Acta,1969
5. N-Hydroxylation: A new metabolic reaction observed in the rat with the carcinogen 2-acetylaminofluorene;Cramer;J. Biol. Chem.,1960
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1. Sex hormone-mediated effects on the phase I and phase II metabolism of N-2-fluorenylacetamide;Biochemical Pharmacology;1989-04
2. Modifications of Hepatic Microsomal 9-Oxidation ofN-2-Fluorenylacetamide in Response to Gonadectomy and Treatment of Rats with Phenobarbital or Diethylnitrosamine;Xenobiotica;1989-01
3. Lipid peroxide catalyzed chemical carcinogenesis;Journal of the American Oil Chemists' Society;1984-12
4. Effects of metyrapone on microsomal-dependent Salmonella mutagenesis;Biochemical Pharmacology;1983-12
5. Kinetic evidence for the involvement of multiple forms of human liver cytochrome P-450 in the metabolism of acetylaminofluorene;Carcinogenesis;1983
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