Reducing Biotechnological Risks

Author:

Vallero Daniel A.

Publisher

Elsevier

Reference54 articles.

1. The commission is responsible for health and safety regulation in Great Britain. The health and safety executive and local government are the enforcing authorities who work in support of the commission;United Kingdom Health and Safety Commission,1998

2. The concept of “reasonableness” is a constant theme of this book. Unfortunately, the means of determining reasonable designs are open to interpretation. The legal community uses the reasonable person standard. Professional ethics review boards may also indirectly apply such a standard. The reasonable person is akin to Immanuel Kant's categorical imperative. [Kant, Immanuel; translated by James W. Ellington [1785] (1993). Grounding for the Metaphysics of Morals 3rd ed. Hackett. p. 30. ISBN 0-87220-166-X]. That is, if act (e.g. approach to the design) were universalized, would this be perceived be a “good” or “bad” approach? This is type of query where reviewers might ask whether the designer “knew or should have known” the adverse aspects of the design in advance.

3. United Kingdom Health and Safety Commission.

4. The term “intangible” is quite interesting in modern vernacular. First, it is one of those adjectives that have morphed into a noun. It is often used in sports analyses, such as when the University of North Carolina plays Duke University in the Atlantic Coast Conference championship. UNC may have taller and more gifted players in a given year. They may also have home-court advantage, a deeper bench, and momentum. However, sportscasters may say that Duke has the “intangible advantage”. This seems to consist of variables that defy quantitation or even objective analysis. If Duke goes on to win the game, the analysts may do their best retrospectively to deconstruct these intangibles (e.g. it was exam week, UNC players distracted because they were on the cover of Sports Illustrated, traffic on Highway 15–501, premature bonfires on Franklin Street, etc.). However, such weightings were not possible before the game; This is similar to risk assessment and perception. The value of information may be that the perceptions were correct, but the actual process by which they led to the correct risk assessment are not well understood. The deconstruction of these processes can lead to better risk assessments next time (lessons learned) if the factors can be identified. Thus, a retrospective sensitivity analysis can inform future risk-based decision models; Next time, we will know better why Duke won. In this sense, Coach K (Duke's famous coach Krzyzewski) is a risk analyst who is applying sound science to decide how to handle the UNC Tar Heels’ next visit to the Cameron Stadium on Duke's campus.

5. Appendix E: risk quotient method and LOCs – risks of metolachlor use to federally listed endangered Barton Springs salamander;The following discussion is based on: U.S. Environmental Protection Agency,2007

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