Fragment-Based Approaches to the Discovery of Kinase Inhibitors

Author:

Mortenson Paul N.,Berdini Valerio,O’Reilly Marc

Publisher

Elsevier

Reference81 articles.

1. Ligand efficiency indices as guideposts for drug discovery;Abad-Zapatero;Drug Discovery Today,2005

2. Kinase-targeted libraries: The design and synthesis of novel, potent, and selective kinase inhibitors;Akritopoulou-Zanze;Drug Discovery Today,2009

3. Selectivity of kinase inhibitor fragments;Bamborough;Journal of Medicinal Chemistry,2011

4. The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901;Barrett;Bioorganic & Medicinal Chemistry Letters,2008

5. Ligand efficiency and fragment-based drug discovery;Bembenek;Drug Discovery Today,2009

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