Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats

Author:

Boyce S.,Webb J. K.,Shepheard S. L.,Russell M. G.N.,Hill R. G.,Rupniak N. M.J.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Anesthesiology and Pain Medicine,Neurology (clinical),Neurology

Reference22 articles.

1. ABT-594 (R)-5-(2-azetidinylmethoxy)-2-chloropyridine: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization.;Bannon;J Pharmacol Exp Ther,1998

2. Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors.;Bannon;Science,1998

3. Role of the nucleus raphe magnus in antinociception produced by ABT-594: immediate early gene responses possibly linked to neuronal nicotinic acetylcholine receptors on serotonergic neurons.;Bitner;J Neurosci,1998

4. Frog venom cocktail yields a one-handed painkiller.;Bradley;Science,1993

5. Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice.;Decker;Eur J Pharmacol,1998

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