Key metrics to expanding the pipeline of successful antibody–drug conjugates
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference59 articles.
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2. A HER2-targeting antibody–drug conjugate, trastuzumab deruxtecan (DS-8201a), enhances antitumor immunity in a mouse model;Iwata;Mol. Cancer Ther.,2018
3. Monoclonal antibody therapy of solid tumors: clinical limitations and novel strategies to enhance treatment efficacy;Cruz;Biologics,2019
4. Quantitative pharmacology in antibody–drug conjugate development: armed antibodies or targeted small molecules?;Nessler;Oncoscience,2018
5. Antibody–drug conjugates bearing pyrrolobenzodiazepine or tubulysin payloads are immunomodulatory and synergize with multiple immunotherapies;Rios-Doria;Cancer Res.,2017
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