Li–Fraumeni Syndrome Disease Model: A Platform to Develop Precision Cancer Therapy Targeting Oncogenic p53

Author:

Zhou Ruoji,Xu An,Gingold Julian,Strong Louise C.,Zhao Ruiying,Lee Dung-Fang

Funder

University of Texas Health Science Center at Houston

National Institutes of Health

Cancer Prevention and Research Institute of Texas

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference238 articles.

1. Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome;Li;J. Natl. Cancer Inst.,1969

2. Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?;Li;Ann. Intern. Med.,1969

3. A cancer family syndrome in twenty-four kindreds;Li;Cancer Res.,1988

4. Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li–Fraumeni families;Birch;Cancer Res.,1994

5. Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers;Nichols;Cancer Epidemiol. Biomarkers Prev.,2001

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